1-Piperidinecarboxylic acid, 4-(4-carboxy-1H-1,2,3-triazol-1-yl)-, 1-(1,1-dimethylethyl) ester
1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid
CAS: 1119452-31-1
Molecular Formula: C13H20N4O4
1-Piperidinecarboxylic acid, 4-(4-carboxy-1H-1,2,3-triazol-1-yl)-, 1-(1,1-dimethylethyl) ester - Names and Identifiers
1-Piperidinecarboxylic acid, 4-(4-carboxy-1H-1,2,3-triazol-1-yl)-, 1-(1,1-dimethylethyl) ester - Physico-chemical Properties
| Molecular Formula | C13H20N4O4 |
| Molar Mass | 296.32 |
| Density | 1.36±0.1 g/cm3(Predicted) |
| Boling Point | 487.8±55.0 °C(Predicted) |
| pKa | 3.31±0.50(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD12027299 |
1-Piperidinecarboxylic acid, 4-(4-carboxy-1H-1,2,3-triazol-1-yl)-, 1-(1,1-dimethylethyl) ester - Risk and Safety
| Hazard Class | IRRITANT |
1-Piperidinecarboxylic acid, 4-(4-carboxy-1H-1,2,3-triazol-1-yl)-, 1-(1,1-dimethylethyl) ester - Introduction
1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid is an organic compound. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C15H21N5O4
-Molecular weight: 343.36g/mol
-Melting point: 165-167°C
-Solubility: Soluble in organic solvents such as chloroform and carbon disulfide
Use:
- 1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid can be widely used as an organic synthetic intermediate in pharmaceutical synthesis and biochemical research.
-It can be used as a precursor of anti-tumor, anti-inflammatory, antibacterial and other drugs, and can also be used to prepare biologically active compounds or fluorescent probes.
Preparation Method:
- 1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid can be synthesized by a variety of synthetic routes, one of the commonly used methods is the reaction of piperidin-4-amine with tert-butylcarbonate in the presence of tert-butanol, followed by the preparation of 1-(1-tert-butoxycarbonyl) piperidine-4-methanol by reaction with 1,2, 3-trichloroacetone. Finally, the target product is obtained by reaction with 1,2, 3-triazole-4-carboxylic acid.
Safety Information:
- 1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid has limited toxicity information, but it can be expected that it may be irritating.
-Laboratory safety practices should be followed, and protective laboratory procedures should be performed to avoid contact with skin and inhalation.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective masks when using.
Please note that anyone using chemical reagents in a laboratory or industrial environment should first carefully read and understand the chemical safety data sheet, and operate under appropriate equipment and environmental conditions.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C15H21N5O4
-Molecular weight: 343.36g/mol
-Melting point: 165-167°C
-Solubility: Soluble in organic solvents such as chloroform and carbon disulfide
Use:
- 1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid can be widely used as an organic synthetic intermediate in pharmaceutical synthesis and biochemical research.
-It can be used as a precursor of anti-tumor, anti-inflammatory, antibacterial and other drugs, and can also be used to prepare biologically active compounds or fluorescent probes.
Preparation Method:
- 1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid can be synthesized by a variety of synthetic routes, one of the commonly used methods is the reaction of piperidin-4-amine with tert-butylcarbonate in the presence of tert-butanol, followed by the preparation of 1-(1-tert-butoxycarbonyl) piperidine-4-methanol by reaction with 1,2, 3-trichloroacetone. Finally, the target product is obtained by reaction with 1,2, 3-triazole-4-carboxylic acid.
Safety Information:
- 1-[1-(tert-Butoxycarbonyl)piperidin-4-yl]-1H-1,2,3-triazole-4-carboxylic acid has limited toxicity information, but it can be expected that it may be irritating.
-Laboratory safety practices should be followed, and protective laboratory procedures should be performed to avoid contact with skin and inhalation.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective masks when using.
Please note that anyone using chemical reagents in a laboratory or industrial environment should first carefully read and understand the chemical safety data sheet, and operate under appropriate equipment and environmental conditions.
Last Update：2024-04-09 21:00:56
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